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Use of selective serotonin inhibitors may

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increase the risk of gastrointestinal bleeding in patients taking aspirin, nonsteroidal antiinflammatory drugs, and other drugs that cause bleeding. Some neurotransmitters that are released do not bind to receptors and are taken

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up by the nerves that produced them. Short-term studies

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did not show an increase in the risk of suicidality with antidepressants compared with placebo in adults beyond 24 years of anesthesiology pain medicine should be closely observed

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for clinical worsening, suicidality, or unusual changes in behavior.. The usual starting

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dose of escitalopram is 10 mg once daily in the morning or evening. Benefit may not be seen until treatment has been given for up to 4 weeks. Drugs in the SSRI class also have been studied in persons with obsessive compulsive disorders and panic disorders, but escitalopram

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is not approved for this neuropathic pain relief purpose. Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in short-term studies in children and adolescents with depression and other psychiatric disorders. Neurotransmitters are made and released by nerves

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and then travel

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to other nearby nerves where they attach to receptors on the nerves. All SSRIs, including escitalopram, should not be combined with drugs in the monoamine oxidase (MAO) inhibitor class of antidepressants such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl) and procarbazine (Matulane). Conversely, at least 14 days should elapse after discontinuing an MAO inhibitor before starting escitalopram. In order

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to avoid these symptoms, the dose of SSRI can be slowly reduced instead of abruptly stopped. Therefore, escitalopram should not be used during

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pregnancy unless, in the opinion of the physician, the expected benefits to the patient outweigh unknown hazards to the fetus. SSRIs work by affecting neurotransmitters in

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the brain, the chemical messengers that nerves use to communicate with one another. Escitalopram should not be given to nursing mothers unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards

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to the child. Escitalopram is an oral drug that is used for treating depression and generalized anxiety disorder. Anyone considering the use of escitalopram or

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any other antidepressant in a child or adolescent must balance this risk with the clinical need. Chemically, escitalopram is similar to citalopram (Celexa). Symptoms may include dizziness, tingling, tiredness, vivid dreams, irritability, or poor mood. Both are in the class of drugs called selective serotonin reuptake inhibitors (SSRIs), a class that also includes fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft). In particular, about one in 11 men given escitalopram report difficulties ejaculating. The FDA approved escitalopram in August

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2002. There was a reduction in risk of suicidality with antidepressants compared with placebo in adults 65 years of age and older. This is referred to as "reuptake." Many experts believe that an imbalance of neurotransmitters is the cause of depression. The dose may be increased to 20 mg once daily after 1 week.

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Some patients experience withdrawal reactions upon stopping SSRI therapy. Escitalopram can be taken with or without food.

Although changes in sexual desire, sexual performance, and sexual satisfaction often occur as a result of depression

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itself, they also may be a consequence of the drugs used to treat depression. Tryptophan can cause headaches, nausea, sweating, and dizziness when taken with any SSRI. The most com side effects associated with escitalopram are agitation or restlessness, blurred vision, diarrhea, difficulty sleeping, drowsiness, dry mouth, fever, frequent urination, headache, indigestion, nausea, increased or decreased appetite, increased sweating, sexual difficulties (decreased sexual ability or desire, ejaculatory delay), taste alterations, tremor (shaking), weight changes. Escitalopram is excreted in

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human milk. Escitalopram is approved for the treatment of depression and generalized anxiety disorder. The safety of escitalopram during pregnancy and breastfeeding has not been established. Escitalopram prevents the reuptake of one neurotransmitter, serotonin, by nerves, an action which results in more serotonin in the brain to attach to receptors.

Escitalopram should be stored at room temperature, 15-30 C (59-86 F) PRESCRIBED FOR. Such combinations may lead to confusion, high blood pressure, high fevers, tremor or muscle rigidity, and increased activity.